Seems like pretty powerful stuff. If it's not helping I think you can still take zzzquil along with it (since zzz doesn't have much medicine along with it other than the sleepy stuff) but I would ask your doctor first. I can tell you that you can take zzz with alcohol and still be ok the next morning. Or extra zzz. (or THC but you can take THC with anything and be dandy) But other than that I'm pretty clueless what it can be mixed with.