Physically, migraines. I get them once a week or so, and it's hell. It's always debilitating and if it gets really bad I even get nauseous and vomit from it. I can't go to the doctor right now to get it checked out, so I'm just kind of stuck with this horrible pain whenever it strikes.
Emotionally...god. So many. Besides general emotional suffering from depression, someone very special to me whom I loved with all my heart hurt me a lot over the course of our friendship/relationship and never returned my affections. I think the unrequited love is what has been the worst pain I've ever felt. That paired with the jealousy of the girl he did love. I know that sounds generic but when it's WAY more than just a crush, and it's true, genuine love, the heart wrenching pain in your chest is unbearable. Thankfully time heals, but I still have waves where the hurt from the situation comes back and I feel like I could just die from the pain.